tert-Butyl (3R)-3-(hydroxymethyl)pyrrolidine-1-carboxylate → tert-butyl 3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidine-1-carboxylate
Reaktionsgleichung
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:14][CH:11]([CH2:12][OH:13])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3].[CH3:15][n:16]1[n:31][cH:30][c:18]([NH:19][c:20]2[n:29][c:28]([c:23]3[c:22](Cl)[n:21]2)[nH:27][cH:26][c:24]3[Cl:25])[cH:17]1>>[CH3:15][n:16]1[n:31][cH:30][c:18]([NH:19][c:20]2[n:29][c:28]([c:23]3[c:22]([O:13][CH2:12][CH:11]4[CH2:14][N:8]([C:6]([O:5][C:2]([CH3:4])([CH3:3])[CH3:1])=[O:7])[CH2:9][CH2:10]4)[n:21]2)[nH:27][cH:26][c:24]3[Cl:25])[cH:17]1Komponenten
7
