Water → 2-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole

HRID 2051768Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2051768
[CH3:1][S:2][C:3]1[NH:7][C:6]2[CH:8]=[C:9]3[C:14](=[CH:15][C:5]=2[N:4]=1)[CH:13]=[CH:12][CH:11]=[CH:10]3.SC[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1.O>C(O)C>[N:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[CH2:1][S:2][C:3]1[NH:4][C:5]2[CH:15]=[C:14]3[C:9](=[CH:8][C:6]=2[N:7]=1)[CH:10]=[CH:11][CH:12]=[CH:13]3

Komponenten

5

Edukt 3

HCID 962WaterHCID 2560712-PyridinemethanethiolHCID 128720792-(methylthio)-1H-naphtho[2,3-d]imidazole

Produkt 1

HCID 223941842-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazoleAusbeute 81,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

0.45 g of 2-methylthio-1H-naphth[2,3-d]imidazole and 0.64 g of 2-mercaptomethylpyridine were heated for 40 hours under reflux in 10 ml of ethanol. 10 ml of water were added to the homogeneous solution and the precipitate formed was filtered off. 0.50 g of 2-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole having a m.p. of 170° was obtained.

Aufarbeitung

  1. customthe precipitate formed
  2. filtrationwas filtered off

Quellen und Nachweise

ORD-Eintrag
ord-8cffeb46b0b14b5395d8e0e24fdbc492
Quelldatensatz
uspto-grants-1980_01
Patentnummer
US04182766

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