3-(Trifluoromethyl)aniline → N-methyl-6-(6-methyl-3-(3-(trifluoromethyl)phenylamino)benzo[d]isothiazol-7-yl)quinazolin-2-amine

Reaktionsgleichung

[NH2:1][C:2]1[C:6]2[CH:7]=[CH:8][C:9]([CH3:23])=[C:10]([C:11]3[CH:12]=[C:13]4[C:18](=[CH:19][CH:20]=3)[N:17]=[C:16]([NH:21][CH3:22])[N:15]=[CH:14]4)[C:5]=2[S:4][N:3]=1.[F:24][C:25]([F:34])([F:33])[C:26]1[CH:27]=[C:28](N)[CH:29]=[CH:30][CH:31]=1.CC(C1C=C(C(C)C)C(C2C=CC=CC=2P(C2CCCCC2)C2CCCCC2)=C(C(C)C)C=1)C.CC(C)([O-])C.[Na+]>C(OCC)(=O)C.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd].C1(C)C=CC=CC=1>[CH3:22][NH:21][C:16]1[N:15]=[CH:14][C:13]2[C:18](=[CH:19][CH:20]=[C:11]([C:10]3[C:5]4[S:4][N:3]=[C:2]([NH:1][C:30]5[CH:29]=[CH:28][CH:27]=[C:26]([C:25]([F:34])([F:33])[F:24])[CH:31]=5)[C:6]=4[CH:7]=[CH:8][C:9]=3[CH3:23])[CH:12]=2)[N:17]=1