1-Methylimidazole → HCID 70387076, Verbindung

HRID 2119222Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2119222
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:6]=1[CH3:12])=[O:4].[CH3:13][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1>C(OCC)C>[Br-:1].[CH3:13][NH+:14]1[CH:18]=[CH:17][N:16]([CH2:2][C:3]([C:5]2[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:6]=2[CH3:12])=[O:4])[CH2:15]1

Komponenten

4

Edukt 2

HCID 13901-MethylimidazoleHCID 20634502-Bromo-1-(2,4-dimethylphenyl)ethanone

Produkt 1

HCID 70387076HCID 70387076, VerbindungAusbeute 51 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

A solution of 4.76 g (0.021 mol) of 1-bromo-2-(2,4-dimethylphenyl)-2-oxoethane and 1.76 g (0.021 mol) of 1-methylimidazole in 50 ml of diethyl ether was stirred at room temperature for approximately 21 hours. The reaction solvent was decanted and the residue was washed with diethyl ether. The residue was recrystallized from acetonitrile/ethyl acetate to afford 3.32 g of the title product as white crystals. (51% yield) mp=179°-181° C.

Aufarbeitung

  1. customThe reaction solvent was decanted
  2. washthe residue was washed with diethyl ether
  3. customThe residue was recrystallized from acetonitrile/ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-de65f7ca93cf426faa8057562c722a00
Quelldatensatz
uspto-grants-1987_07
Patentnummer
US04683312

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