Pyridine → 4-[[8-[(4-Methylphenyl)sulfonyl]octyl]oxy]-1,1-biphenyl

HRID 2165061Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2165061
[C:1]1([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:6]=[CH:5][C:4]([O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]O)=[CH:3][CH:2]=1.[S:23](Cl)([C:26]1[CH:32]=[CH:31][C:29]([CH3:30])=[CH:28][CH:27]=1)(=[O:25])=[O:24].N1C=CC=CC=1>O>[CH3:30][C:29]1[CH:31]=[CH:32][C:26]([S:23]([CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][O:7][C:4]2[CH:5]=[CH:6][C:1]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:2][CH:3]=2)(=[O:25])=[O:24])=[CH:27][CH:28]=1

Komponenten

5

Edukt 3

HCID 1049PyridineHCID 73974-Toluenesulfonyl chlorideHCID 139591154-(8-Hydroxyoctyl)oxybiphenyl

Produkt 1

HCID 230435324-[[8-[(4-Methylphenyl)sulfonyl]octyl]oxy]-1,1-biphenyl

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 33.26 g of 8-([1,1'-biphenyl]-4-yloxy)-1-octanol, 23.37 g of tosyl chloride and 200 ml of pyridine was allowed to stand in a refrigerator overnight. Then water was added, the solid collected, washed with water and dissolved in chloroform. This solution was washed with dilute hydrochloric acid then saturated aqueous sodium bicarbonate, dried and the solvent removed, giving the desired compound as a white solid.

Aufarbeitung

  1. customto stand in a refrigerator overnight
  2. customthe solid collected
  3. washwashed with water
  4. dissolutiondissolved in chloroform
  5. washThis solution was washed with dilute hydrochloric acid
  6. dry with materialsaturated aqueous sodium bicarbonate, dried
  7. customthe solvent removed

Quellen und Nachweise

ORD-Eintrag
ord-70e98206962349cebf1c09a0baac64ff
Quelldatensatz
uspto-grants-1990_07
Patentnummer
US04939127

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