Nitric Acid → 3-nitro-9-isopropyl-9H-carbazole

HRID 2184930Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2184930
[CH:1]([N:4]1[C:16]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2)([CH3:3])[CH3:2].[N+:17]([O-])([OH:19])=[O:18].O>CC(O)=O>[CH:1]([N:4]1[C:16]2[CH:15]=[CH:14][C:13]([N+:17]([O-:19])=[O:18])=[CH:12][C:11]=2[C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2)([CH3:3])[CH3:2]

Komponenten

5

Edukt 3

HCID 944Nitric AcidHCID 962WaterHCID 738739H-Carbazole, 9-(1-methylethyl)-

Produkt 1

HCID 6174713-nitro-9-isopropyl-9H-carbazoleAusbeute 87 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel2×

Versuchsvorschrift

A solution of 9-Isopropyl-9H-carbazole (Acros, 1.5 9, 7.2 mmol) in AcOH (50 ml) was treated dropwise with a solution of nitric acid (3.35 ml) in AcOH (10 mL) over 30 minutes. When the reaction was complete the mixture was poured into water and stirred for 15 minutes, then the solid filtered and washed with Et2O to afford the desired product as a solid (1.6 g, 87%).

Aufarbeitung

  1. filtrationthe solid filtered
  2. washwashed with Et2O

Quellen und Nachweise

ORD-Eintrag
ord-fc95bb89ea3c446d8d28849dd4eddc91
Quelldatensatz
uspto-grants-2002_06
Patentnummer
US06399631B1

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