Bromide ion → 1-(2-Methoxyethenyl)-4-(1-methylbutyloxy)benzene

HRID 21887Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 21887
C([Li])CCC.[Br-].[CH3:7][CH:8]([O:12][C:13]1[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=1)[CH2:9][CH2:10][CH3:11].[O:21]1[CH2:25]CC[CH2:22]1>CCCCCC>[CH3:22][O:21][CH:25]=[CH:17][C:16]1[CH:19]=[CH:20][C:13]([O:12][CH:8]([CH3:7])[CH2:9][CH2:10][CH3:11])=[CH:14][CH:15]=1

Komponenten

6

Edukt 4

HCID 259Bromide ionHCID 8028Tetrahydrofuran2×HCID 199306244-(1-Methylbutyloxy)benzaldehydeHCID 178418339Butyllithium

Produkt 1

HCID 537267651-(2-Methoxyethenyl)-4-(1-methylbutyloxy)benzene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8058HexaneLösungsmittel

Versuchsvorschrift

A solution containing butyllithium dissolved in hexane was added to a solution containing 120 g of methoxymethyltriphenylphosphoni bromide dissolved in tetrahydrofuran (THF), in an atmosphere of argon, and the mixture was stirred for one hour at room temperature. A solution of the compound (30) dissolved in THF was added thereto and stirring was continued for two hours. The reaction solution was washed with water, was dried over magnesium sulfate, and was then concentrated. The residue was purified by column chromatography to obtain 1-(2-methoxyethenyl)-4-(1-methylbutyloxy)benzene (31).

Aufarbeitung

  1. additionwas added to a solution
  2. additionwas added
  3. stirringstirring
  4. waitwas continued for two hours
  5. washThe reaction solution was washed with water
  6. dry with materialwas dried over magnesium sulfate
  7. concentrationwas then concentrated
  8. customThe residue was purified by column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-c98de13488664eb499e8466680457ad6
Quelldatensatz
uspto-grants-1995_06
Patentnummer
US05425897

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