Fluoroethane → Propanoyl fluoride, 3,3,3-trifluoro-2-(trifluoromethyl)-

HRID 2198385Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2198385
[Al+3].[Cl-].[Cl-].[Cl-].[CH:5]([C:14]([O:17]CC)(F)[F:15])([C:10]([F:13])([F:12])[F:11])[C:6]([F:9])([F:8])[F:7].C(F)C>C(C(Cl)=O)(C(F)(F)F)C(F)(F)F.C(OCC)C>[CH:5]([C:14]([F:15])=[O:17])([C:6]([F:8])([F:7])[F:9])[C:10]([F:13])([F:12])[F:11]

Komponenten

6

Edukt 3

HCID 9620FluoroethaneHCID 5336551-Ethoxy-1,1,3,3,3-pentafluoro-2-(trifluoromethyl)propaneHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 181462Propanoyl fluoride, 3,3,3-trifluoro-2-(trifluoromethyl)-Ausbeute 36,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 128097393,3,3-Trifluoro-2-(trifluoromethyl)propionyl chlorideKatalysatorHCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

The above ethyl ether, 43 g (0.175 mol), in a 100 ml flask equipped as described in Example 6 was mixed with 1 g (0.0075 mol) of AlCl3. The mixture was refluxed for 17 hours. Material condensed in the attached Dry Ice-acetone trap was combined with residual material in the flask and distilled in a low-temperature still. An amount of 30.8 g of unreacted (CF3)2CHCF2OC2H5 was recovered, together with 9.1 g (26.3% yield) of (CF3)2CHCOF, 2.2 g of C2H5F and 0.1 g of (CF3)2CHCOCl. No improvement in product yield was obtained when the reactants were heated in a sealed tube at 120° for 4 hours.

Aufarbeitung

  1. temperatureThe mixture was refluxed for 17 hours
  2. customMaterial condensed in the
  3. distillationdistilled in a low-temperature still

Quellen und Nachweise

ORD-Eintrag
ord-a5fe1dae238441a19145063728062f47
Quelldatensatz
uspto-grants-1982_11
Patentnummer
US04357282

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