Acetic Anhydride → N-(4-Fluoro-2-methylphenyl)acetamide
Reaktionsgleichung
[F:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([CH3:9])[CH:3]=1.[O:10](C(C)=O)[C:11]([CH3:13])=O>>[F:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:11](=[O:10])[CH3:13])=[C:4]([CH3:9])[CH:3]=1Komponenten
3
Versuchsvorschrift
A mixture of 4-fluoro-2-methylaniline (20 g) and (CH3CO)2O (400 mL) was stirred at RT for 3 hours. The reaction mixture was subsequently poured into ice water (1000 mL), stirred for 10 minutes, filtered, and dried under vacuum to give the title compound (20 g, 74%).
Aufarbeitung
- stirringstirred for 10 minutes
- filtrationfiltered
- customdried under vacuum
Quellen und Nachweise
- ORD-Eintrag
- ord-259c4edab98645ea991b35ce6b268676
- Quelldatensatz
- uspto-grants-2016_06
- Patentnummer
- US09365566B2
Notizen zur Reaktion
Wird geladen…