4-Amino-2-hydroxy-5-nitrobenzoic acid → 4,5-Diamino-2-hydroxybenzoic acid

HRID 2205118Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2205118
[NH2:1][C:2]1[C:10]([N+:11]([O-])=O)=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([OH:14])[CH:3]=1>CC(O)=O.[Pd]>[NH2:1][C:2]1[C:10]([NH2:11])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([OH:14])[CH:3]=1

Komponenten

4

Edukt 1

HCID 218421914-Amino-2-hydroxy-5-nitrobenzoic acid

Produkt 1

HCID 131586084,5-Diamino-2-hydroxybenzoic acid

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

Under an H2(g) atmosphere, a suspension of 4-amino-2-hydroxy-5-nitrobenzoic acid (200 mg, 1.01 mmol, 1.00 equiv) and Pd/C (anhydrous) (0.1 g) in HOAc (15 mL) in a 50-mL round-bottom flask was allowed to react, with stirring, overnight at room temperature. The resulting solution was directly taken on to the next step without further purification.

Aufarbeitung

  1. customto react
  2. customThe resulting solution was directly taken on to the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-c8e11cca5aa645de84043ab848f77ef1
Quelldatensatz
uspto-grants-2016_06
Patentnummer
US09370522B2

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