1,2-Dichloroethane → HCID 71525879, Verbindung

HRID 2205252

Reaktionsgleichung

C[C:2](C)(C(C)=C)[C:3](=[O:5])C.[NH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11]1.N1[C:27]2[C:22](=[CH:23]C=C[CH:26]=2)[CH2:21]C=1.Cl[Sn](Cl)(Cl)Cl.Cl[CH2:34]CCl>>[CH3:34][C:27](=[C:22]([CH3:21])[CH3:23])[CH2:26][CH:11]1[CH2:12][C:13]2[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:10]1[C:3](=[O:5])[CH3:2]

Komponenten

Edukt 5

HCID 111,2-Dichloroethane

HCID 798Indole

HCID 24287Tin tetrachloride

HCID 30835603H-Indole

HCID 132625373,3,4-Trimethylpent-4-en-2-one

Produkt 1

HCID 71525879HCID 71525879, VerbindungAusbeute 58 %

Versuchsvorschrift

Following the general procedure as described in Example 11, 3,3,4-trimethylpent-4-en-2-one (0.50 g, 3.96 mmol), 1H-indole (0.56 g, 4.75 mmol) which was in situ isomerized to 3H-indole, and SnCl4 (1.24 g, 4.75 mmol) in 1,2-dichloroethane (40 ml) were reacted to give the title product as a white solid (0.56 g, 58%).

Aufarbeitung

customwere reacted

Quellen und Nachweise

ORD-Eintrag: ord-cfeb19e361a74c21b17c8dd50fedbe70
Quelldatensatz: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US09371262B2

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