Phthalic Anhydride → HCID 178514955, Verbindung

HRID 2205840Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2205840
[C:1]1([C:7]2[CH:11]=[C:10]([NH2:12])[NH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:13]1(=O)[O:18][C:16](=[O:17])[C:15]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]12>C(O)(=O)C.O>[C:1]1([C:7]2[CH:11]=[C:10]([N:12]3[C:16](=[O:17])[C:15]4[C:14](=[CH:22][CH:21]=[CH:20][CH:19]=4)[C:13]3=[O:18])[NH:9][N:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

5

Edukt 2

HCID 6811Phthalic AnhydrideHCID 1366553-Amino-5-phenylpyrazole

Produkt 1

HCID 178514955HCID 178514955, VerbindungAusbeute 91 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 176Acetic AcidLösungsmittelHCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
120 °C

Versuchsvorschrift

A mixture of 3-phenyl-1H-pyrazol-5-amine (6 g, 0.038 mol), phthalic anhydride (5.6 g, 0.038 mol) in acetic acid (60 mL) was heated at 100° C. for 2 h and at 120° C. for 2 h and cooled to room temperature. The reaction mixture was diluted with water and the suspension was filtered. The collected solid was washed with water, dried, yielding the title compound as a solid (10 g).

Aufarbeitung

  1. temperaturecooled to room temperature
  2. filtrationthe suspension was filtered
  3. washThe collected solid was washed with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-32d385edf1954820916da020f56e2a70
Quelldatensatz
uspto-grants-2016_06
Patentnummer
US09371332B2

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