Hydrochloric Acid → HCID 19375560, Verbindung

HRID 2211134Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2211134
[ClH:1].Cl.C1(C=[N:10][N:11]2[CH2:15][C:14](=[O:16])[N:13]([CH2:17][CH2:18][CH2:19][CH2:20][N:21]3[CH2:26][CH2:25][N:24]([CH3:27])[CH2:23][CH2:22]3)[C:12]2=[O:28])C=CC=CC=1.Cl.[H][H]>[Pd].O>[ClH:1].[NH2:10][N:11]1[CH2:15][C:14](=[O:16])[N:13]([CH2:17][CH2:18][CH2:19][CH2:20][N:21]2[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]2)[C:12]1=[O:28]

Komponenten

6

Edukt 3

HCID 313Hydrochloric AcidHCID 70171685HCID 70171685, VerbindungHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 19375560HCID 19375560, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 1-phenylmethyleneamino-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione dihydrochloride (8.04 g, 0.0187 mole), 2N HCl (125 ml) and 5% Pd/C:50% H2O (1.5 g, is subjected to hydrogen on a Parr apparatus at 40 psi at ambient temperature. After 2 hours, the catalyst is removed by filtration. The filtrate is divided into two equal portions. Each is concentrated under reduced pressure on a rotary evaporator to an oily residue of 1-amino-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione hydrochloride.

Aufarbeitung

  1. customthe catalyst is removed by filtration
  2. concentrationEach is concentrated under reduced pressure on a rotary evaporator to an oily residue of 1-amino-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione hydrochloride

Quellen und Nachweise

ORD-Eintrag
ord-fc9a978f69ab4a168084b2cf93544975
Quelldatensatz
uspto-grants-1995_10
Patentnummer
US05462940

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