Water → 2-Ethylamino-3-nitropyridine
Reaktionsgleichung
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH2:11]([NH2:13])[CH3:12].O>C1COCC1>[CH2:11]([NH:13][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1)[CH3:12]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of 2-chloro-3-nitropyridine (51 g, 325 mmol) in THF (650 mL) was added a 2 M solution of ethylamine in THF (365 mL, 731 mmol). The reaction was stirred at room temperature overnight. The reaction mixture was poured into water (˜1.5 L) and the resulting solid was filtered and dried under reduced pressure to give the title compound (52 g).
Aufarbeitung
- filtrationthe resulting solid was filtered
- customdried under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-6dbf7c26a3a34e8b80800167216e79d0
- Quelldatensatz
- uspto-grants-2002_07
- Patentnummer
- US06420359B1
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