Isopropylamine → HCID 14990558, Verbindung

HRID 2248309Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2248309
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[O:9])=[CH:4][C:3]=1[N+:17]([O-:19])=[O:18].[CH3:20][CH:21]([NH2:23])[CH3:22]>O>[F:16][C:13]1[CH:14]=[CH:15][C:10]([C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:23][CH:21]([CH3:22])[CH3:20])=[C:3]([N+:17]([O-:19])=[O:18])[CH:4]=2)=[O:9])=[CH:11][CH:12]=1

Komponenten

4

Edukt 2

HCID 6363IsopropylamineHCID 30155644-Chloro-4'-fluoro-3-nitrobenzophenone

Produkt 1

HCID 14990558HCID 14990558, VerbindungAusbeute 97,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A solution of 14 parts of (4-chloro-3-nitrophenyl) (4-fluorophenyl)-methanone in 69 parts of 2-propanamine was stirred overnight at reflux temperature. The reaction mixture was poured into water. The precipitate was filtered off and washed with water, dried, filtered and evaporated, yielding 14.7 parts (97.2%) of (4-fluorophenyl) [4-[(1-methylethyl)-amino]-3-nitrophenyl]methanone as a residue (int. 1).

Aufarbeitung

  1. temperatureat reflux temperature
  2. filtrationThe precipitate was filtered off
  3. washwashed with water
  4. customdried
  5. filtrationfiltered
  6. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-14fbbd2795cd443084668a93f1c7d33e
Quelldatensatz
uspto-grants-1991_08
Patentnummer
US05039677

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