4-Nitrobenzamide → 4-Aminobenzamide
Reaktionsgleichung
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH2:10])=[O:9])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH2:10])=[O:9])=[CH:6][CH:5]=1Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
In 100 ml of absolute ethanol, 8.35 g of the compound of Example II was hydrogenated over 2 spatulas-full of 10% Pd/C in a Parr apparatus at ca 40 lbs/in2 for 3-4 hrs. Under a nitrogen blanket, the catalyst was filtered off through a Celite pad (sintered glass funnel), which was washed with two volumes of ethanol. Evaporation gave ca 7.2 g of a brown oil.
Aufarbeitung
- customin2 for 3-4 hrs
- filtrationUnder a nitrogen blanket, the catalyst was filtered off through a Celite pad (sintered glass funnel), which
- washwas washed with two volumes of ethanol
- customEvaporation
Quellen und Nachweise
- ORD-Eintrag
- ord-3b2ae0a86cb24970997363fb693d602b
- Quelldatensatz
- uspto-grants-1980_11
- Patentnummer
- US04235969
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