Benzene → 2,2-Dimethyl-3-heptanoyl oxazolidine

HRID 225228

Reaktionsgleichung

Reaktionsgleichung von HRID 225228
C1C=CC=CC=1.[CH3:7][C:8]1([CH3:13])[NH:12][CH2:11][CH2:10][O:9]1.C(N(CC)CC)C.[C:21](Cl)(=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>O>[CH3:7][C:8]1([CH3:13])[N:12]([C:21](=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:11][CH2:10][O:9]1

Komponenten

6

Edukt 4

HCID 241Benzene2×HCID 8471TriethylamineHCID 17313Heptanoyl chlorideHCID 5506972,2-Dimethyl-oxazolidine

Produkt 1

HCID 129067982,2-Dimethyl-3-heptanoyl oxazolidine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Sixteen and one-half (16.5 ml.) milliliters of a benzene solution containing 4.6 g. of 2,2-dimethyl oxazolidine was added to 50 ml. of benzene and 4.1 g. of triethylamine. To this mixture 6 g. of n-heptanoyl chloride was added dropwise with stirring and cooling in an ice bath. The mixture was poured into water and the benzene layer extracted, dried over magnesium sulfate and the benzene removed under vacuum. Yield was 7.5 g. of an oil, nD30 =1.4598.

Aufarbeitung

  1. temperaturecooling in an ice bath
  2. extractionthe benzene layer extracted
  3. dry with materialdried over magnesium sulfate
  4. customthe benzene removed under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-39e1f6b09b71420ca16b1f1bbe89257c
Quelldatensatz
uspto-grants-1980_11
Patentnummer
US04236011

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