Butyrophenone → 2-Bromo-1-phenylbutan-1-one

HRID 2263195Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2263195
[C:1]1([C:7](=[O:11])[CH2:8][CH2:9][CH3:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:12]Br>C(OCC)C>[Br:12][CH:8]([CH2:9][CH3:10])[C:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:11]

Komponenten

4

Edukt 2

HCID 10315ButyrophenoneHCID 24408Bromine

Produkt 1

HCID 526962-Bromo-1-phenylbutan-1-oneAusbeute 72,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

To a solution of 1-phenylbutan-1-one (10.0 g, 67.5 mmol) in diethyl ether (200 ml) was slowly added dropwise bromine (10.8 g, 67.5 mmol), and the mixture was stirred at room temperature for 4 hours. The reaction solution was distilled off under reduced pressure to give the desired product (11.1 g, 72.3%) as an oil.

Aufarbeitung

  1. distillationThe reaction solution was distilled off under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-a2e3b55f8b6a453fbae25d2af1e6283f
Quelldatensatz
uspto-grants-2010_12
Patentnummer
US07851473B2

Notizen zur Reaktion

Wird geladen…