Toluene → 2-Methacryloyloxy-4,4-dimethyl-gamma-butyrolactone

HRID 2305281

Reaktionsgleichung

[OH:1][CH:2]1[CH2:7][C:6]([CH3:9])([CH3:8])[O:5][C:3]1=[O:4].[C:10](Cl)(=[O:14])[C:11]([CH3:13])=[CH2:12].C(N(CC)CC)C.C1(C)C=CC=CC=1>O>[C:10]([O:1][CH:2]1[CH2:7][C:6]([CH3:9])([CH3:8])[O:5][C:3]1=[O:4])(=[O:14])[C:11]([CH3:13])=[CH2:12]

Komponenten

Reaktionsbedingungen

Temperatur: 25 °C

Versuchsvorschrift

A mixture of 100 mmole of the above-prepared 2-hydroxy4,4-dimethyl-γ-butyrolactone, 150 mmole of methacrylic chloride, 150 mmole of triethylamine, and 300 ml of toluene was stirred at 25° C. for 4 hours. Water was added to the reaction mixture, the organic layer was then concentrated, and the concentrate was subjected to column chromatography on a silica gel to yield 2-methacryloyloxy-4,4-dimethyl-γ-butyrolactone in a yield of 85%.

Aufarbeitung

concentrationthe organic layer was then concentrated

Quellen und Nachweise

ORD-Eintrag: ord-d4b53fe675724568b381d4c716ec6c72
Quelldatensatz: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06440636B1

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