4,4'-Dihydroxybiphenyl → 4'-(2-Methylbutoxy)(1,1'-biphenyl)-4-ol

HRID 231005

Reaktionsgleichung

Reaktionsgleichung von HRID 231005
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH3:15][CH:16]([CH2:19][CH3:20])[CH2:17]Br.C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH3:15][CH:16]([CH2:19][CH3:20])[CH2:17][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1

Komponenten

5

Edukt 3

HCID 71124,4'-DihydroxybiphenylHCID 11430Potassium CarbonateHCID 252541-Bromo-2-methylbutane

Produkt 1

HCID 140938154'-(2-Methylbutoxy)(1,1'-biphenyl)-4-olAusbeute 58 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 0.20 mole(37.2 g) of 4,4'-dihydroxybiphenyl, 0.10 mole(15.1 g) of the above 2-methyl-1-bromobutane, and 0.60 mole(33.7 g) of potassium carbonate in 300 ml of ethanol was refluxed for 16 hours. After the reaction, the reaction solution was filtered and concentrated, then purified by column chromatography to obtain 4.9 g of 4'-(2-methylbutoxy)-4-hydroxybiphenyl. (yield: 58%)

Aufarbeitung

  1. customAfter the reaction
  2. filtrationthe reaction solution was filtered
  3. concentrationconcentrated
  4. custompurified by column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-7579d4eec5224c2fa2bdb88004109b17
Quelldatensatz
uspto-grants-1989_07
Patentnummer
US04844835

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