4-Hydroxybenzoic Acid → 4-(1-Methylheptyloxycarbonyl)phenol

HRID 231025

Reaktionsgleichung

Reaktionsgleichung von HRID 231025
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[CH3:11][C@@H:12](O)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].S(=O)(=O)(O)O>C1C=CC=CC=1>[CH3:11][CH:12]([O:7][C:6](=[O:8])[C:5]1[CH:9]=[CH:10][C:2]([OH:1])=[CH:3][CH:4]=1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Komponenten

5

Edukt 3

HCID 1354-Hydroxybenzoic AcidHCID 1118Sulfuric AcidHCID 80080(R)-2-Octanol

Produkt 1

HCID 110103794-(1-Methylheptyloxycarbonyl)phenolAusbeute 43 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

27.6 g of p-hydroxybenzoic acid and 39.0 g of (R)-2-octanol were refluxed for 10 hours in 300 ml of benzene in the presence of 0.5 ml of conc. sulfuric acid. Then, the reaction solution was cooled to the room temperature, and then concentrated and purified by column chromatography, to obtain 21.5 g of p-hydroxybenzoic acid 1-methylheptyl ester. (yield: 43%)

Aufarbeitung

  1. concentrationconcentrated
  2. custompurified by column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-9a63337d10b54f90af339903302db2f4
Quelldatensatz
uspto-grants-1989_07
Patentnummer
US04844835

Verknüpfte Notizen

Wird geladen…