Dimethyl Sulfoxide → 2-[2-[2-[1-(5-Chloropyrimidin-2-yl)piperidin-4-yl]cyclopropyl]ethylamino]-6-methylpyridine-4-carbonitrile
Reaktionsgleichung
[CH3:36][S:37]([CH3:38])=[O:39].[Cl:1][c:2]1[cH:3][n:4][c:5]([N:8]2[CH2:9][CH2:10][CH:11]([CH:14]3[CH:15]([CH2:17][CH2:18][NH2:19])[CH2:16]3)[CH2:12][CH2:13]2)[n:6][cH:7]1.[Cl:26][c:27]1[cH:28][c:29]([C:30]#[N:31])[cH:32][c:33]([CH3:35])[n:34]1.[K+:20].[K+:21].[O-:22][C:23]([O-:24])=[O:25].[OH2:40]>>[Cl:1][c:2]1[cH:3][n:4][c:5]([N:8]2[CH2:9][CH2:10][CH:11]([CH:14]3[CH:15]([CH2:17][CH2:18][NH:19][c:27]4[cH:28][c:29]([C:30]#[N:31])[cH:32][c:33]([CH3:35])[n:34]4)[CH2:16]3)[CH2:12][CH2:13]2)[n:6][cH:7]1
