Hydrochloric Acid → N-{5-[(2-{[(2,2-difluorocyclopropyl)carbonyl]amino]imidazo[1,2-b]pyridazin-6-yl)oxy]-2-methylphenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide

HRID 2349545

Reaktionsgleichung

Reaktionsgleichung von HRID 2349545
[CH3:49][N:50]([CH3:51])[C:52](=[O:53])[CH3:54].[CH3:55][N:56]([CH3:57])[CH:58]=[O:59].[Cl:14][C:15]([C:16]([Cl:17])=[O:18])=[O:19].[ClH:20].[F:1][C:2]1([F:8])[CH:3]([C:5](=[O:6])[OH:7])[CH2:4]1.[NH2:21][c:22]1[n:23][c:24]2[n:25]([n:26][c:27]([O:30][c:31]3[cH:32][cH:33][c:34]([CH3:47])[c:35]([NH:37][C:38](=[O:39])[c:40]4[cH:41][c:42]([CH3:46])[n:43][n:44]4[CH3:45])[cH:36]3)[cH:28][cH:29]2)[cH:48]1.[O:9]1[CH2:10][CH2:11][CH2:12][CH2:13]1>>[F:1][C:2]1([F:8])[CH:3]([C:5](=[O:6])[NH:21][c:22]2[n:23][c:24]3[n:25]([n:26][c:27]([O:30][c:31]4[cH:32][cH:33][c:34]([CH3:47])[c:35]([NH:37][C:38](=[O:39])[c:40]5[cH:41][c:42]([CH3:46])[n:43][n:44]5[CH3:45])[cH:36]4)[cH:28][cH:29]3)[cH:48]2)[CH2:4]1

Komponenten

8

Edukt 7

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 31374DimethylacetamideHCID 65578Oxalyl chlorideHCID 27828232,2-Difluorocyclopropane-1-carboxylic acidHCID 57505636N-[5-(2-aminoimidazo[1,2-b]pyridazin-6-yl)oxy-2-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide

Produkt 1

HCID 57505634N-{5-[(2-{[(2,2-difluorocyclopropyl)carbonyl]amino]imidazo[1,2-b]pyridazin-6-yl)oxy]-2-methylphenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide

Quellen und Nachweise

ORD-Eintrag
ord-8679b7103b94443bbec701c54154c7b8
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Verknüpfte Notizen

Wird geladen…