Sodium Acetate → 7-(2-Chlorophenyl)[1,2,4]triazolo[4,3-b][1,2,4]triazine

HRID 237089Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 237089
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]([CH:10]=O)=O.[NH2:12][C:13]1[N:17]([NH2:18])[CH:16]=[N:15][N:14]=1.C([O-])(=O)C.[Na+]>C(O)(=O)C>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:10]=[N:18][N:17]2[CH:16]=[N:15][N:14]=[C:13]2[N:12]=1

Komponenten

5

Edukt 3

HCID 517045Sodium AcetateHCID 5671443,4-Diamino-1,2,4-triazoleHCID 124638862-Chlorophenylglyoxal

Produkt 1

HCID 30545047-(2-Chlorophenyl)[1,2,4]triazolo[4,3-b][1,2,4]triazine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

A solution of 14 g. of o-chlorophenylglyoxal, 10.6 g. of 3,4-diamino-4H-1,2,4-triazole and 6.3 g. of sodium acetate in 180 ml. of 67% acetic acid is heated on a steam bath and then filtered through celite. The filtrate is heated for an additional hour and then allowed to stand at room temperature for several days, producing the desired product as a cream colored solid, m.p. 162°-165° C.

Aufarbeitung

  1. filtrationfiltered through celite
  2. temperatureThe filtrate is heated for an additional hour
  3. waitto stand at room temperature for several days

Quellen und Nachweise

ORD-Eintrag
ord-d3540f074033467aab8879e2104eebcf
Quelldatensatz
uspto-grants-1979_06
Patentnummer
US04159375

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