Benzaldehyde → 2-Methyl-N-(phenylmethylene)-2-propanamine

HRID 2399929Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2399929
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9]([NH2:13])([CH3:12])([CH3:11])[CH3:10]>O>[CH:1](=[N:13][C:9]([CH3:12])([CH3:11])[CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 240BenzaldehydeHCID 6385Tert-Butylamine

Produkt 1

HCID 1112402-Methyl-N-(phenylmethylene)-2-propanamineAusbeute 88,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To a three neck round bottom flask, equipped with a cold water condenser, 30 g of water and 26.5 g of benzaldehyde were added. The mixture was mixed with a magnetic stirrer at room temperature for 3 minutes. t-Butyl amine (22.1 g) was added to the reaction flask in one portion, followed by vigorous stirring for 15 hours. The agitation was stopped and the reaction mixture was allowed to stand for at least 15 minutes. The lower aqueous layer was separated from the reaction mixture. The upper layer was collected and dried over magnesium sulfate to give 35.5 g of product. 1H NMR (300 Hz, CDCl3, ppm): 8.29 (1H, s), 7.77 (2H, m), 7.40 (3H, m), 1.33 (9H, s).

Aufarbeitung

  1. customTo a three neck round bottom flask, equipped with a cold water condenser
  2. additionThe mixture was mixed with a magnetic stirrer at room temperature for 3 minutes
  3. waitto stand for at least 15 minutes
  4. customThe lower aqueous layer was separated from the reaction mixture
  5. customThe upper layer was collected
  6. dry with materialdried over magnesium sulfate

Quellen und Nachweise

ORD-Eintrag
ord-29f50643f535465cab600c3c04e42f1e
Quelldatensatz
uspto-grants-1995_09
Patentnummer
US05451653

Notizen zur Reaktion

Wird geladen…