Acetic Acid → HCID 54127815, Verbindung

HRID 2413451Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2413451
C[O-].[Na+].[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=O.[CH3:18][C:19]([C:21]1[CH:22]=[CH:23][C:24]([OH:27])=[CH:25][CH:26]=1)=O.[Cl-].C1([PH+](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(O)(=O)C>CO.C(O)C>[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=[CH:18][CH2:19][C:21]1[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=1

Komponenten

7

Edukt 4

HCID 176Acetic AcidHCID 10942334Sodium MethoxideHCID 13090787HCID 13090787, VerbindungHCID 86741956HCID 86741956, Verbindung

Produkt 1

HCID 54127815HCID 54127815, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 887MethanolLösungsmittel

Reaktionsbedingungen

Temperatur
20 °C

Versuchsvorschrift

36 ml of a 15% strength solution of sodium methylate in methanol were added to 11 g of 3,7-dichloro-8-formylquinoline and 21.6 g of 4-hydroxyacetophenone-triphenylphosphonium chloride in 150 ml of ethanol. The mixture was stirred for 21/2 hours at 20° C., after which 3 ml of glacial acetic acid were added and the precipitate was filtered off under suction, washed with water and dried.

Aufarbeitung

  1. filtrationthe precipitate was filtered off under suction
  2. washwashed with water
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-e7e2b04f662f42a8a83157e311725dcc
Quelldatensatz
uspto-grants-1988_01
Patentnummer
US04717416

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