1-Aminocyclopropane-1-carboxylic acid → 1-[(n-{[4-((2r,3r)-1-(4-Fluorophenyl)-3-{[2-(4-fluorophenyl)-2-hydroxyethyl]thio}-4-oxoazetidin-2-yl)phenoxy]acetyl}glycyl)amino]cyclopropanecarboxylic acid

Reaktionsgleichung

CN1CCOCC1.CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F.[F:30][C:31]1[CH:36]=[CH:35][C:34]([N:37]2[C:40](=[O:41])[C@H:39]([S:42][CH2:43][C:44]([C:46]3[CH:51]=[CH:50][C:49]([F:52])=[CH:48][CH:47]=3)=[O:45])[C@H:38]2[C:53]2[CH:67]=[CH:66][C:56]([O:57][CH2:58][C:59]([NH:61][CH2:62][C:63](O)=[O:64])=[O:60])=[CH:55][CH:54]=2)=[CH:33][CH:32]=1.[NH2:68][C:69]1([C:72]([OH:74])=[O:73])[CH2:71][CH2:70]1.[BH4-].[Na+]>CN(C=O)C.CO>[F:30][C:31]1[CH:32]=[CH:33][C:34]([N:37]2[C:40](=[O:41])[C@H:39]([S:42][CH2:43][CH:44]([C:46]3[CH:47]=[CH:48][C:49]([F:52])=[CH:50][CH:51]=3)[OH:45])[C@H:38]2[C:53]2[CH:54]=[CH:55][C:56]([O:57][CH2:58][C:59]([NH:61][CH2:62][C:63]([NH:68][C:69]3([C:72]([OH:74])=[O:73])[CH2:71][CH2:70]3)=[O:64])=[O:60])=[CH:66][CH:67]=2)=[CH:35][CH:36]=1