Water → 3-Amino-2,6-dimethylphenol

HRID 258958

Reaktionsgleichung

Reaktionsgleichung von HRID 258958
[CH3:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][CH:5]=[C:4]([CH3:11])[C:3]=1[OH:12].O.C(=O)([O-])[O-].[Na+].[Na+]>[Fe].C(O)(=O)C>[NH2:8][C:7]1[C:2]([CH3:1])=[C:3]([OH:12])[C:4]([CH3:11])=[CH:5][CH:6]=1

Komponenten

6

Edukt 3

HCID 962WaterHCID 10340Sodium CarbonateHCID 814763-Nitro-2,6-xylenol

Produkt 1

HCID 814773-Amino-2,6-dimethylphenolAusbeute 62 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23925IronKatalysatorHCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

157 g (0.94 mole) of 2,6-dimethyl-3-nitro phenol is added little by little, while stirring, to a reducing mixture consisting of 950 cm3 of water, 30 cm3 of acetic acid and 158 g of iron, which has first been heated to 70°. When this addition has been completed, the heating is continued for 20 minutes. The reaction mixture is then neutralized with sodium carbonate and the boiling liquid is filtered. After cooling the filtrate, drying yields 80 g of 3-amino-2,6-dimethyl phenol which, after recrystallization in benzene, melts at 104°.

Aufarbeitung

  1. temperaturehas first been heated to 70°
  2. additionWhen this addition
  3. filtrationthe boiling liquid is filtered
  4. temperatureAfter cooling the filtrate
  5. customdrying

Quellen und Nachweise

ORD-Eintrag
ord-8ba5f60dc77743459513b68ac7f17a38
Quelldatensatz
uspto-grants-1977_07
Patentnummer
US04035422

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