Tetrahydrofuran → Maltol
Reaktionsgleichung
[O:1]1CCCC1.BrBr.[O:8]1[CH:12]=[CH:11][CH:10]=[C:9]1[CH:13]([OH:15])[CH3:14]>O>[CH3:14][C:13]1[O:15][CH:12]=[CH:11][C:10](=[O:1])[C:9]=1[OH:8]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 10 °C
Versuchsvorschrift
To a 4-neck round bottom flask equipped with a thermometer, a condensor and two addition funnels was charged 50 ml of tetrahydrofuran and 50 ml of water and the solution was cooled to 10° C. To this well stirred solution was added together in the two addition funnels bromine (0.20 mole) and 1(2-furyl)-1-ethanol (0.09 mole). The temperature of the reaction was maintained at 15° C. throughout the double addition. The reaction mixture was then heated to 75° C. for 10 hours. Maltol was isolated by the procedure of Example 1 (53% yield).
Aufarbeitung
- customTo a 4-neck round bottom flask equipped with a thermometer
- additiona condensor and two addition funnels
- temperatureThe temperature of the reaction was maintained at 15° C. throughout the double addition
- temperatureThe reaction mixture was then heated to 75° C. for 10 hours
Quellen und Nachweise
- ORD-Eintrag
- ord-86108ece6be54748bf031644ae43cd30
- Quelldatensatz
- uspto-grants-1979_04
- Patentnummer
- US04147705
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