Sodium borohydride → N-(o-Chlorobenzyl)-2-methyl-3-chloroaniline

HRID 261823Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 261823
[Cl:1][C:2]1[CH:17]=[CH:16][CH:15]=[CH:14][C:3]=1[CH:4]=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([Cl:12])[C:7]=1[CH3:13].[BH4-].[Na+]>CO.O>[Cl:1][C:2]1[CH:17]=[CH:16][CH:15]=[CH:14][C:3]=1[CH2:4][NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([Cl:12])[C:7]=1[CH3:13]

Komponenten

5

Edukt 2

HCID 4311764Sodium borohydrideHCID 13017551N-(o-Chlorobenzylidene)-2-methyl-3-chloroaniline

Produkt 1

HCID 21321344N-(o-Chlorobenzyl)-2-methyl-3-chloroaniline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

A suspension of N-(o-chlorobenzylidene)-2-methyl-3-chloroaniline (0.038 mole) is brought to reflux in 100 cc of absolute methanol. An equivalent of sodium borohydride (1.5 g.) is added in portions and refluxing is continued for 15 mins. The reaction mixture is cooled and diluted with an equal volume of cold water to precipitate a solid. This material is collected, washed with H2O and air dried. Recrystallization from ethanol gives N-(o-Chlorobenzyl)-2-methyl-3-chloroaniline. m.p. 63°-66° C.

Aufarbeitung

  1. temperaturerefluxing
  2. temperatureThe reaction mixture is cooled
  3. customto precipitate a solid
  4. customThis material is collected
  5. washwashed with H2O and air
  6. customdried
  7. customRecrystallization from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-7a8529161f27459898c0d6297c3f8657
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04152452

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