Ethanol → HCID 21320301, Verbindung

HRID 262224Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 262224
[H-].[Na+].C(O)C.[CH3:6][SH:7].Br[CH2:9][C:10]1[CH:11]=[CH:12][C:13]2[O:17][C:16]([N+:18]([O-:20])=[O:19])=[C:15]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:14]=2[CH:27]=1>O>[CH3:6][S:7][CH2:9][C:10]1[CH:11]=[CH:12][C:13]2[O:17][C:16]([N+:18]([O-:20])=[O:19])=[C:15]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:14]=2[CH:27]=1

Komponenten

6

Edukt 4

HCID 702EthanolHCID 878MethanethiolHCID 24758Sodium hydrideHCID 13531604HCID 13531604, Verbindung

Produkt 1

HCID 21320301HCID 21320301, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To a stirred mixture of 1.4 g. of sodium hydride in 150 ml. of ethanol is added 6 ml. of methyl mercaptan, then 6.6 g. (0.02 mole) of 5-bromomethyl-2-nitro-3-phenylbenzofuran. After four hours the mixture is poured into cold water, this mixture is extracted with diethyl ether, the extracts are washed with 5 percent sodium hydroxide solution, water and saturated sodium chloride solution, then dried. Evaporation provides yellow 5-methylthiomethyl-2-nitro-3-phenylbenzofuran. The structural assignment is supported by infrared spectral analysis.

Aufarbeitung

  1. additionTo a stirred mixture of 1.4 g
  2. extractionthis mixture is extracted with diethyl ether
  3. washthe extracts are washed with 5 percent sodium hydroxide solution, water and saturated sodium chloride solution
  4. customdried
  5. customEvaporation

Quellen und Nachweise

ORD-Eintrag
ord-935ee0a50e4a45fa93a60c2fe8e59114
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04153716

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