Potassium Carbonate → 2-(1H-Imidazol-1-yl)-1-(2-naphthalenyl)ethanone

HRID 26545

Reaktionsgleichung

Reaktionsgleichung von HRID 26545
Cl.[CH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[C:12]([CH2:14][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1)=[O:13].C(=O)([O-])[O-].[K+].[K+]>CCOCC>[CH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[C:12]([CH2:14][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1)=[O:13]

Komponenten

4

Edukt 2

HCID 11430Potassium CarbonateHCID 51199Nafimidone monohydrochloride

Produkt 1

HCID 512002-(1H-Imidazol-1-yl)-1-(2-naphthalenyl)ethanone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

1-(2-Naphthoylmethyl)imidazole hydrochloride (1.0 g.) suspended in 50 ml. of ether is stirred with excess dilute aqueous potassium carbonate solution until the salt is completely dissolved. The organic layer is then separated, washed twice with water, dried over magnesium sulfate and evaporated to yield 1-(2-naphthoylmethyl)imidazole.

Aufarbeitung

  1. dissolutionis completely dissolved
  2. customThe organic layer is then separated
  3. washwashed twice with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-db5c8d01e01c4b6882b725e1358bba66
Quelldatensatz
uspto-grants-1979_04
Patentnummer
US04150153

Verknüpfte Notizen

Wird geladen…