Cyclopropylamine → HCID 28390698, Verbindung

HRID 270065

Reaktionsgleichung

Reaktionsgleichung von HRID 270065
[OH:1][C:2]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=O.[CH:14]1([NH2:17])[CH2:16][CH2:15]1>>[CH:14]1([NH:17][C:4](=[O:6])[C:3]2[CH:8]=[CH:9][C:10]([O:12][CH3:13])=[CH:11][C:2]=2[OH:1])[CH2:16][CH2:15]1

Komponenten

3

Edukt 2

HCID 69828CyclopropylamineHCID 79523Methyl 4-methoxysalicylate

Produkt 1

HCID 28390698HCID 28390698, Verbindung

Versuchsvorschrift

A suspension of methyl 2-hydroxy-4-methoxybenzoate (5.1 g, 28.0 mmol) in cyclopropyl amine 24 mL) was stirred at room temperature for 5 days. The volatiles were removed in vacuo and the residue was purified by silica gel flash chromatography (0-60% ethyl acetate in petroleum ether) to give the subtitled compound (1.8 g).

Aufarbeitung

  1. customThe volatiles were removed in vacuo
  2. customthe residue was purified by silica gel flash chromatography (0-60% ethyl acetate in petroleum ether)

Quellen und Nachweise

ORD-Eintrag
ord-28b3b4d48a0f4850b7c740c5ce9c9a29
Quelldatensatz
uspto-grants-2008_11
Patentnummer
US07449475B2

Verknüpfte Notizen

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