Water → Calcium 3-(4,6-dimethoxypyrimidin-2-yl)oxy-6-dimethylaminopicolinate

HRID 274879Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 274879
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([O:11][C:12]2[C:13]([C:21]([O-:23])=[O:22])=[N:14][C:15]([N:18]([CH3:20])[CH3:19])=[CH:16][CH:17]=2)[N:4]=1.[K+].C(=O)([O-])[O-].[Ca+2:29].O>O1CCCC1>[CH3:10][O:9][C:7]1[CH:8]=[C:3]([O:2][CH3:1])[N:4]=[C:5]([O:11][C:12]2[C:13]([C:21]([O-:23])=[O:22])=[N:14][C:15]([N:18]([CH3:19])[CH3:20])=[CH:16][CH:17]=2)[N:6]=1.[Ca+2:29].[CH3:10][O:9][C:7]1[CH:8]=[C:3]([O:2][CH3:1])[N:4]=[C:5]([O:11][C:12]2[C:13]([C:21]([O-:23])=[O:22])=[N:14][C:15]([N:18]([CH3:19])[CH3:20])=[CH:16][CH:17]=2)[N:6]=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 10112Calcium CarbonateHCID 23710069Potassium 3-(4,6-dimethoxypyrimidin-2-yl)oxy-6-dimethylaminopicolinate

Produkt 1

HCID 23221890Calcium 3-(4,6-dimethoxypyrimidin-2-yl)oxy-6-dimethylaminopicolinate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

1.0 g (3.1 mmol) of potassium 3-(4,6-dimethoxypyrimidin-2-yl)oxy-6-dimethylaminopicolinate was dissolved in 10 ml of tetrahydrofuran, and 0.15 g (1.5 mmol) of precipitated calcium carbonate was added thereto. Furthermore, 10 ml of water was added to the resultant mixture, and the mixture was stirred at room temperature. The reaction liquor was concentrated under reduced pressure, and acetone was added thereto to precipitate a crystal. The crystal thus obtained was separated by filtration and was washed with hexane to obtain an aimed compound.

Aufarbeitung

  1. concentrationThe reaction liquor was concentrated under reduced pressure, and acetone
  2. additionwas added
  3. customto precipitate a crystal
  4. customThe crystal thus obtained
  5. customwas separated by filtration
  6. washwas washed with hexane

Quellen und Nachweise

ORD-Eintrag
ord-88201f79872b4fd9a82dc9ab8aab7ed7
Quelldatensatz
uspto-grants-1995_02
Patentnummer
US05391537

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