Benzaldehyde → Heptanophenone

HRID 276161

Reaktionsgleichung

Reaktionsgleichung von HRID 276161
[CH:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.NC1C(C)=CC=CN=1.N[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.C(O)(=O)C1C=CC=CC=1.C=CCCCC.C1(C)C=CC=CC=1>>[C:1]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)(=[O:8])[CH2:22][CH2:23][CH2:18][CH2:19][CH2:20][CH3:21]

Komponenten

7

Edukt 6

HCID 240BenzaldehydeHCID 243Benzoic AcidHCID 1140TolueneHCID 6115AnilineHCID 115971-HexeneHCID 153472-Amino-3-methylpyridine

Produkt 1

HCID 74282Heptanophenone

Reaktionsbedingungen

Temperatur
130 °C

Versuchsvorschrift

Under the same reaction procedure and conditions as in Example 1 (benzaldehyde 0.5 mmol, 2-amino-3-picoline 0.1 mmol, aniline 0.3 mmol, bezoic acid 0.03 mmol, 1-hexene 2.5 mmol, toluene 0.87 mmol), the mixture in a 500 ml pressure reactor was stirred at normal temperature for 2-3 minutes and then various transition metal catalysts as shown in the following table 6 were added to each reactor. While the reactor was stopped with a stopper, the reactants were heated at 130° C. for 1 hour with stirring. After completion of the reaction, gas chromatography was conducted to determine the yields of heptanophenone, products according to various transition metal catalysts. The results are shown in Table 6, below.

Aufarbeitung

  1. additionwere added to each reactor
  2. stirringwith stirring
  3. customAfter completion of the reaction, gas chromatography

Quellen und Nachweise

ORD-Eintrag
ord-0b2b3a60d24044dfbcbd6ee1f35c0342
Quelldatensatz
uspto-grants-2002_03
Patentnummer
US06353139B1

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