Water → HCID 54408223, Verbindung

HRID 277294

Reaktionsgleichung

Reaktionsgleichung von HRID 277294
[C:1]([C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=[O:7])#[N:2].[CH3:11][C:12]([C:14]1[CH:19]=[C:18]([C:20]#[N:21])[CH:17]=[CH:16][CH:15]=1)=O.OS(O)(=O)=O.O>C(O)(=O)C>[C:20]([C:18]1[CH:19]=[C:14]([CH:12]=[CH:11][C:6]([C:5]2[CH:8]=[CH:9][CH:10]=[C:3]([C:1]#[N:2])[CH:4]=2)=[O:7])[CH:15]=[CH:16][CH:17]=1)#[N:21]

Komponenten

6

Edukt 4

HCID 962WaterHCID 1118Sulfuric AcidHCID 802223-AcetylbenzonitrileHCID 90670m-Formylbenzonitrile

Produkt 1

HCID 54408223HCID 54408223, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

3-Cyanobenzaldehyde (3.0 g, 23.0 mmol) and 3-cyanoacetophenone (3.34 g, 23.0 mmol) in glacial acetic acid (5 mL) and concentrated H2SO4 (3.66 mL, 69 mmol) was stirred at room temperature for 72 hours. Water (200 mL) was added and the reaction filtered. The precipitate was washed with water (2×200 mL) and dried in vacuo to give 3,3′-dicyanochalcone as an off-white solid. MS (APCI) m/z 258 (M+−1, 100%). 13C NMR (50 MHz, d6-DMSO): δ111.7, 117.8, 118.0, 123.0, 129.7, 131.6, 132.1, 132.4, 133.3, 133.5, 135.3, 136.1, 137.4, 142.1, 187.3.

Aufarbeitung

  1. filtrationthe reaction filtered
  2. washThe precipitate was washed with water (2×200 mL)
  3. customdried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-14ffe8cfbb58484792efb5d5d57e1733
Quelldatensatz
uspto-grants-2002_03
Patentnummer
US06355683B1

Verknüpfte Notizen

Wird geladen…