2-Phenylisobutyric acid → 2-Methyl-2-phenylpropanoyl chloride
Reaktionsgleichung
[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[C:3](O)=[O:4].C(Cl)(=O)C([Cl:16])=O>ClCCl>[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[C:3]([Cl:16])=[O:4]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A solution of 2-Methyl-2-phenylpropionic acid (10 mmol, 1.0 eq.) and oxalyl chloride (40 mmol, 4.0 eq.) in dichloromethane (30 mL) was stirred at room temperature for 18 h. The mixture was concentrated in vacuo to afford the title compound as a yellow oil.
Aufarbeitung
- concentrationThe mixture was concentrated in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-b388f55835f0450eb8040b6671d8a7a3
- Quelldatensatz
- uspto-grants-2008_09
- Patentnummer
- US07420055B2
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