Thiophosgene → HCID 178440816, Verbindung
Reaktionsgleichung
[C:1]([C:5]1[CH:6]=[C:7]([NH2:11])[CH:8]=[CH:9][CH:10]=1)([CH3:4])([CH3:3])[CH3:2].C(=O)(O)[O-].[Na+].C(Cl)(Cl)=[S:18]>CC(C)=O>[N-:11]=[C:7]=[S:18].[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To 3-(tert-butyl)phenylamine in acetone at 0° C. was added sodium bicarbonate (2 eq) and thiophosgene (2 eq). The mixture was brought to ambient temperature and concentrated and partitioned between ethyl acetate and water. The organic layer was dried with sodium bicarbonate and sodium sulfate and concentrated to yield 3-(tert-butyl)benzenisothiocyanate. MS: MH+=192.
Aufarbeitung
- customwas brought to ambient temperature
- concentrationconcentrated
- custompartitioned between ethyl acetate and water
- dry with materialThe organic layer was dried with sodium bicarbonate and sodium sulfate
- concentrationconcentrated
Quellen und Nachweise
- ORD-Eintrag
- ord-5c2f9b6dcb724652b0a751510608c005
- Quelldatensatz
- uspto-grants-2008_09
- Patentnummer
- US07423150B2
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