Thiophosgene → HCID 178440816, Verbindung

HRID 30794

Reaktionsgleichung

Reaktionsgleichung von HRID 30794
[C:1]([C:5]1[CH:6]=[C:7]([NH2:11])[CH:8]=[CH:9][CH:10]=1)([CH3:4])([CH3:3])[CH3:2].C(=O)(O)[O-].[Na+].C(Cl)(Cl)=[S:18]>CC(C)=O>[N-:11]=[C:7]=[S:18].[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Komponenten

5

Edukt 3

HCID 10040ThiophosgeneHCID 793343-tert-ButylanilineHCID 516892Sodium Bicarbonate

Produkt 1

HCID 178440816HCID 178440816, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

To 3-(tert-butyl)phenylamine in acetone at 0° C. was added sodium bicarbonate (2 eq) and thiophosgene (2 eq). The mixture was brought to ambient temperature and concentrated and partitioned between ethyl acetate and water. The organic layer was dried with sodium bicarbonate and sodium sulfate and concentrated to yield 3-(tert-butyl)benzenisothiocyanate. MS: MH+=192.

Aufarbeitung

  1. customwas brought to ambient temperature
  2. concentrationconcentrated
  3. custompartitioned between ethyl acetate and water
  4. dry with materialThe organic layer was dried with sodium bicarbonate and sodium sulfate
  5. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-5c2f9b6dcb724652b0a751510608c005
Quelldatensatz
uspto-grants-2008_09
Patentnummer
US07423150B2

Verknüpfte Notizen

Wird geladen…