Water → HCID 10499321, Verbindung

HRID 324020Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 324020
Cl[C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1.O.O.[NH2:29][NH2:30]>>[NH:29]([C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1)[NH2:30]

Komponenten

4

Edukt 3

HCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 10738129HCID 10738129, Verbindung

Produkt 1

HCID 10499321HCID 10499321, Verbindung

Versuchsvorschrift

A suspension of 1-(2-chloro-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (16.0 g) in hydrazine hydrate (50 ml) is refluxed for four hours. The mixture is cooled to room temperature, and then thereto is added water. The precipitated crystals are collected by filtration, washed with water, and dried to give 1-(2-hydrazino-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (14.5 g).

Aufarbeitung

  1. temperatureis refluxed for four hours
  2. filtrationThe precipitated crystals are collected by filtration
  3. washwashed with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-07315e3ab0da4347a10d5e6fe0e4f108
Quelldatensatz
uspto-grants-2001_04
Patentnummer
US06214996B1

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