Lithium hydroxide, monohydrate → CID 53416564

HRID 324406Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 324406
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=[CH:12][C:13]([O:15]C)=[O:14])[CH:6]=[CH:7][CH:8]=1.O.[OH-].[Li+]>CO.O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=[CH:12][C:13]([OH:15])=[O:14])[CH:6]=[CH:7][CH:8]=1

Komponenten

5

Edukt 2

HCID 168937Lithium hydroxide, monohydrateHCID 71366468Methyl 5-(3-methoxyphenyl)penta-2,4-dienoate

Produkt 1

HCID 53416564CID 53416564

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of the product from step (i) (53.2 g) and lithium hydroxide monohydrate (52 g) in methanol (250 ml) and water (100 ml) was stirred at room temperature for 24 hours and partitioned between ethyl acetate and 2M HCl. The organic phase was washed with brine, dried (MgSO4), and evaporated under reduced pressure to afford an orange oil.

Aufarbeitung

  1. custompartitioned between ethyl acetate and 2M HCl
  2. washThe organic phase was washed with brine
  3. dry with materialdried (MgSO4)
  4. customevaporated under reduced pressure
  5. customto afford an orange oil

Quellen und Nachweise

ORD-Eintrag
ord-b14c1bd298ba46eb80b47bab84b4d6c7
Quelldatensatz
uspto-grants-2001_04
Patentnummer
US06218376B1

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