Tobramycin Sulphate Salt → Tobramycin

HRID 326523

Reaktionsgleichung

Reaktionsgleichung von HRID 326523
[CH2:1]1[C@@H:6]([NH2:7])[C@H:5]([O:8][C@H:9]2[O:14][C@H:13]([CH2:15][OH:16])[C@@H:12]([OH:17])[C@H:11]([NH2:18])[C@H:10]2[OH:19])[C@@H:4]([OH:20])[C@H:3]([O:21][C@H:22]2[O:27][C@H:26]([CH2:28][NH2:29])[C@@H:25]([OH:30])[CH2:24][C@H:23]2[NH2:31])[C@H:2]1[NH2:32].OS(O)(=O)=O>O>[CH2:1]1[C@@H:6]([NH2:7])[C@H:5]([O:8][C@H:9]2[O:14][C@H:13]([CH2:15][OH:16])[C@@H:12]([OH:17])[C@H:11]([NH2:18])[C@H:10]2[OH:19])[C@@H:4]([OH:20])[C@H:3]([O:21][C@H:22]2[O:27][C@H:26]([CH2:28][NH2:29])[C@@H:25]([OH:30])[CH2:24][C@H:23]2[NH2:31])[C@H:2]1[NH2:32]

Komponenten

3

Edukt 1

HCID 62005Tobramycin Sulphate Salt

Produkt 1

HCID 36294Tobramycin

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Foam wound materials containing tobramycin sulfate were prepared as shown in Example 1. Once the materials were placed onto grid supports they were maintained at room temperature and covered with a foil wrap. Every 12 hours for nine days, 5 ml of water was applied onto the foam bandage materials and eluent was collected. Two ml samples containing SDMC-entrapped tobramycin were assayed for tobramycin antibiotic activity using standard antimicrobial assays. The results are shown in Table IX.

Aufarbeitung

  1. customwere prepared
  2. customwas collected
  3. additionTwo ml samples containing SDMC-entrapped tobramycin

Quellen und Nachweise

ORD-Eintrag
ord-c938fb36e94549409128815a37398402
Quelldatensatz
uspto-grants-1993_12
Patentnummer
US05269979

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