Lithium Hydroxide → HCID 13708826, Verbindung

HRID 326795Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 326795
[OH-].[Li+].[CH3:3][C:4](=[CH2:13])/[CH:5]=[CH:6]/[CH2:7][C:8]([O:10]CC)=[O:9]>CO.O1CCCC1.O>[CH3:13][C:4](=[CH2:3])/[CH:5]=[CH:6]/[CH2:7][C:8]([OH:10])=[O:9]

Komponenten

6

Edukt 2

HCID 3939Lithium HydroxideHCID 14524662Ethyl trans-4-methyl-2,4-pentadienecarboxylate

Produkt 1

HCID 13708826HCID 13708826, VerbindungAusbeute 76 %

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel2×HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

2.5 g (0.1 mol) of lithium hydroxide are added at 0° C. to 10 g (0.07 mol) of ethyl trans-4-methyl-2,4-pentadienecarboxylate, dissolved in a solvent mixture of 75 ml of methanol, 17 ml of tetrahydrofuran and 2.5 ml of water, and the mixture is stirred for 20 hours at room temperature. After the mixture has been diluted with 200 ml of water, it is extracted once using diethyl ether, and a pH of 1 is established in the aqueous phase at 0° C. using concentrated hydrochloric acid. The mixture is extracted using diethyl ether, the combined organic phases are washed several times with water and saturated sodium chloride solution, and, after drying and concentrating, 6.1 g (76% of theory) of trans-4-methyl-2,4-pentadienecarboxylic acid are obtained. ##STR207##

Aufarbeitung

  1. extractionis extracted once using diethyl ether
  2. customis established in the aqueous phase at 0° C.
  3. extractionThe mixture is extracted
  4. washthe combined organic phases are washed several times with water and saturated sodium chloride solution
  5. customafter drying
  6. concentrationconcentrating

Quellen und Nachweise

ORD-Eintrag
ord-28cbf9e0b02b4c7db2e5e2a4d4e1c4f2
Quelldatensatz
uspto-grants-1993_12
Patentnummer
US05270340

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