Acetic Acid → HCID 19734528, Verbindung
Reaktionsgleichung
[C:1]([C:3]1[CH:7]=[CH:6][O:5][CH:4]=1)#[N:2].C[O-].[Na+].[C:11](O)(=[O:13])C>CO>[O:5]1[CH:6]=[CH:7][C:3]([C:1](=[NH:2])[O:13][CH3:11])=[CH:4]1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
3-cyanofuran (3.76 g, 40.1 mmol) was dissolved in methanol (30 ml), and sodium methoxide (0.1 g, 1.9 mmol) was added. The mixture was stirred at room temperature for 18 hours. After the reaction was completed, acetic acid (0.14 g, 2.3 mmol) was added to neutralize the reaction solution, and the solution was concentrated under reduced pressure. Diethyl ether was added to the concentrated residue, and insolubles were removed by filtration. The filtrate was concentrated under reduced pressure to give the crude product of methyl 3-furancarboximidate as a pale yellow oil.
Aufarbeitung
- concentrationthe solution was concentrated under reduced pressure
- additionDiethyl ether was added to the concentrated residue, and insolubles
- customwere removed by filtration
- concentrationThe filtrate was concentrated under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-eb26a7f163894b7989986efc45870e13
- Quelldatensatz
- uspto-grants-1993_12
- Patentnummer
- US05272164
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