4-Acetamidopyridine acetate → HCID 70155070, Verbindung
Reaktionsgleichung
[C:1]([OH:4])(=[O:3])[CH3:2].[C:5]([NH:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)(=[O:7])[CH3:6].[H][H]>C(O)(=O)C.O=[Pt]=O>[C:1]([OH:4])(=[O:3])[CH3:2].[C:5]([NH:8][CH:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1)(=[O:7])[CH3:6]Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A solution of the product of Example 2 (75 g) in 750 mL acetic acid was reduced over PtO2 catalyst at 60 psi hydrogen atmosphere at 60° C. for 7 hours. The solution was filtered, concentrated and triturated with ether to afford the title compound quantitatively as a white solid which was used directly in subsequent reactions.
Aufarbeitung
- filtrationThe solution was filtered
- concentrationconcentrated
- customtriturated with ether
Quellen und Nachweise
- ORD-Eintrag
- ord-76012d890f2b4e97bf59c6f39a205ece
- Quelldatensatz
- uspto-grants-1991_10
- Patentnummer
- US05053413
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