Water → 3-Benzyl-4-fluorobenzaldehyde

HRID 34604Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 34604
[CH2:1]([C:8]1[CH:9]=[C:10]([CH:15]2OCC[O:16]2)[CH:11]=[CH:12][C:13]=1[F:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O>S(=O)(=O)(O)O.C(OCC)C>[CH2:1]([C:8]1[CH:9]=[C:10]([CH:11]=[CH:12][C:13]=1[F:14])[CH:15]=[O:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

5

Edukt 2

HCID 962WaterHCID 138542792-(3-Benzyl-4-fluorophenyl)-1,3-dioxolane

Produkt 1

HCID 138542803-Benzyl-4-fluorobenzaldehyde

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 1118Sulfuric AcidKatalysatorHCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

A mixture of 2-(3-benzyl-4-fluorophenyl)-1,3-dioxolane (0.7 g) acetone (10 cm3), water (1 cm3) and concentrated sulphuric acid (5 drops) was stirred for 16 hours. The reaction mixture was poured into diethyl ether and the organic layer washed with sodium bicarbonate solution, water and brine, then dried over anhydrous magnesium sulphate. Evaporation of the solvents under reduced pressure gave 3-benzyl-4-fluorobenzaldehdye (0.59 g), which was used without further purification.

Aufarbeitung

  1. washthe organic layer washed with sodium bicarbonate solution, water and brine
  2. dry with materialdried over anhydrous magnesium sulphate
  3. customEvaporation of the solvents under reduced pressure
  4. customgave 3-benzyl-4-fluorobenzaldehdye (0.59 g), which
  5. customwas used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-73f8c703e383498e959b0e486fa1940e
Quelldatensatz
uspto-grants-1988_08
Patentnummer
US04762835

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