Oxygen → 2-Hydroxy4,4-dimethyl-gamma-butyrolactone

HRID 351314

Reaktionsgleichung

Reaktionsgleichung von HRID 351314
C(OCC)(=O)C=C.ON1C(=O)C2=CC=CC=C2C1=O.O=O.[OH:22][CH:23]([CH2:29][C:30]([OH:33])([CH3:32])[CH3:31])[C:24]([O:26]CC)=O>C([O-])(=O)C.[Co+2].C([O-])(=O)C.C(#N)C.CC(O)C>[OH:22][CH:23]1[CH2:29][C:30]([CH3:31])([CH3:32])[O:33][C:24]1=[O:26]

Komponenten

8

Edukt 4

HCID 977OxygenHCID 8821Ethyl AcrylateHCID 10665N-HydroxyphthalimideHCID 11378808Ethyl 2,4-dihydroxy-4-methylpentanoate

Produkt 1

HCID 101977032-Hydroxy4,4-dimethyl-gamma-butyrolactone

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 6277Cobalt diacetateKatalysatorHCID 3776IsopropanolLösungsmittelHCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

A mixture of 3 mmol of ethyl acrylate, 1 ml of 2-propanol, 0.6 mmol of N-hydroxyphthalimide, 0.06 mmol of cobalt(II) acetate, and 1 ml of acetonitrile was stirred at 60° C. in an oxygen atmosphere (1 atm) for 5 hours. A gas chromatographic analysis of products in a reaction mixture revealed that ethyl 2,4-dihydroxy-4-methylpentanoate and α-hydroxy-γ,γ-dimethyl-γ-butyrolactone were formed in yields of 1% and 43%, respectively. The conversion rate from ethyl acrylate was 53%.

Quellen und Nachweise

ORD-Eintrag
ord-b087c489b3d14640bff32dd6289b1d98
Quelldatensatz
uspto-grants-2007_02
Patentnummer
US07183423B1

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