Hydrazine hydrate (1:1) → (Z)-7-Aminohept-5-enoic Acid
Reaktionsgleichung
O.NN.C1(=O)[N:8]([CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][C:15]([OH:17])=[O:16])C(=O)C2=CC=CC=C12>C(O)C.O>[NH2:8][CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][C:15]([OH:17])=[O:16]Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
Hydrazine hydrate (0.19 ml) was added to a solution of (Z)-7-phtalimidohept-5-enoic acid (1.05 g) in ethanol (25 ml) and water (5 ml). The solution was refluxed for 3 hours and then the solvent was removed. The residue was suspended in water and the pH of the solution was adjusted to 5. The resulting precipitate was collected by filtration. The filtrate was evaporated to dryness and extracted with ethanol. The ethanol extracts were evaporated to dryness to give the title compound as an oil (0.62 g).