Anisole → HCID 178503585, Verbindung

HRID 359928Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 359928
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6](=[CH:11][CH:12]=1)[N:7]=[C:8](C)[N:9]=2.[C:13]1(OC)C=CC=CC=1.[F:21][C:22]([F:29])([F:28])[S:23]([O:26]C)(=[O:25])=[O:24]>C(OCC)(=O)C>[F:21][C:22]([F:29])([F:28])[S:23]([O-:26])(=[O:25])=[O:24].[CH3:13][N:7]1[C:6]2=[CH:11][CH:12]=[C:2]([CH3:1])[CH:3]=[CH:4][C:5]2=[NH+:9][CH:8]1[S:23][CH3:22]

Komponenten

5

Edukt 3

HCID 7519AnisoleHCID 9526Methyl triflateHCID 20064366HCID 20064366, Verbindung

Produkt 1

HCID 178503585HCID 178503585, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

27 g of 6-methyl-2-methylcycloheptimidazole was added to 100 ml of anisole and stirred under cooling with ice. Next, 28 g of methyl trifluoromethanesulfonate was dropwise added and further everything was stirred under cooling with ice. After everything was stirred for 1 hour at room temperature, 200 ml of ethyl acetate was added, and the crystals precipitated were separated by filtration and dried.

Aufarbeitung

  1. temperatureunder cooling with ice
  2. stirringfurther everything was stirred
  3. temperatureunder cooling with ice
  4. stirringAfter everything was stirred for 1 hour at room temperature
  5. customthe crystals precipitated
  6. customwere separated by filtration
  7. customdried

Quellen und Nachweise

ORD-Eintrag
ord-372a23129d09481db7728c198ba66752
Quelldatensatz
uspto-grants-1991_03
Patentnummer
US05003077

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