Methanol → 4-[(2-methoxyanilino)methylidene]-5-methyl-2-phenylpyrazol-3-one

HRID 362451

Reaktionsgleichung

Reaktionsgleichung von HRID 362451
[CH3:1][C:2]1[CH2:3][C:4](=[O:13])[N:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:6]=1.[CH:14](OC)(OC)OC.[CH3:21][O:22][C:23]1[C:24]([NH2:29])=[CH:25][CH:26]=[CH:27][CH:28]=1.CO>C(O)(=O)C>[CH3:21][O:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[NH:29][CH:14]=[C:3]1[C:2]([CH3:1])=[N:6][N:5]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:4]1=[O:13]

Komponenten

6

Edukt 4

HCID 887MethanolHCID 4021Mci-186HCID 70002-MethoxyanilineHCID 9005Trimethyl orthoformate

Produkt 1

HCID 1784895884-[(2-methoxyanilino)methylidene]-5-methyl-2-phenylpyrazol-3-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

2 g of 5-methyl-2-phenyl-2,4-dihydro-3-pyrazolone, 188 ml of trimethyl orthoformate and 1.29 ml of o-anisidine are heated with stirring in 5 ml of glacial acetic acid at 70° C. for 2 h. The reaction mixture is cooled and 10 ml of methanol are added. The precipitate which has separated out is filtered off with suction and recrystallized from ethyl acetate.

Aufarbeitung

  1. temperatureThe reaction mixture is cooled
  2. customThe precipitate which has separated out
  3. filtrationis filtered off with suction
  4. customrecrystallized from ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-a5a8ea6e2454456faa5d8fdb3e022197
Quelldatensatz
uspto-grants-1999_02
Patentnummer
US05869516

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