Potassium Carbonate → 1-(2-Hydrazinylethyl)pyrrolidine

HRID 364182

Reaktionsgleichung

Reaktionsgleichung von HRID 364182
O.[NH2:2][NH2:3].Cl.Cl[CH2:6][CH2:7][N:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1.C(=O)([O-])[O-].[K+].[K+].[OH-].[Na+]>O>[NH:2]([CH2:6][CH2:7][N:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1)[NH2:3]

Komponenten

6

Edukt 4

HCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 816681-(2-Chloroethyl)pyrrolidine hydrochloride

Produkt 1

HCID 30315561-(2-Hydrazinylethyl)pyrrolidine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 200 g of 85% hydrazine hydrate, 200 ml of water, 170 g of N-chloroethylpyrrolidine hydrochloride, and 70 g of potassium carbonate was boiled under reflux for seven hours. Sodium hydroxide (390 g) was added and the mixture was extracted with ether. The ethereal extract, dried and distilled, yielded the title compound, bp 107°-111° C. (18.5 mm).

Aufarbeitung

  1. temperatureunder reflux for seven hours
  2. extractionthe mixture was extracted with ether
  3. extractionThe ethereal extract
  4. customdried
  5. distillationdistilled

Quellen und Nachweise

ORD-Eintrag
ord-16204511989e437e8028f0fb62d2c3b9
Quelldatensatz
uspto-grants-1986_08
Patentnummer
US04604390

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